Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CETP | P11597 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491176 | 0.90 | CETP (0.64) | ALDH1A1CETPGAAGFERKDM4E | |
| SCHEMBL8487353 | 0.90 | CETP (0.64) | ALDH1A1CETPGAAGFERKDM4E | |
| SCHEMBL8489836 | 0.90 | CETP (0.61) | ALDH1A1CETPGAAGFERKDM4E | |
| SCHEMBL993229 | 0.86 | CETP (0.71) | ALDH1A1CETPGAAGFERKDM4E | |
| SCHEMBL992553 | 0.86 | CETP (0.71) | ALDH1A1CETPGAAGFERKDM4E | |
| SCHEMBL993028 | 0.86 | CETP (0.71) | ALDH1A1CETPGAAGFERKDM4E | |
| SCHEMBL993442 | 0.86 | CETP (0.71) | ALDH1A1CETPGAAGFERKDM4E | |
| SCHEMBL8491647 | 0.81 | CETP (0.63) | ALDH1A1CETPGAAGFERKDM4E | |
| SCHEMBL8491171 | 0.80 | CETP (0.47) | ALDH1A1CETPGAAGFERKDM4E | |
| SCHEMBL5435254 | 0.79 | GFER (0.78) | ALDH1A1GAAGFERKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999014204-A1 | SUBSTITUTED 1,2,4-TRIAZOLES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | G.D. SEARLE & CO. (US) | 1999-03-25 | — | — | WO | disclosed |