Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1477711 | 0.75 | GRM5 (0.55) | GRM5CHRNB2CHRNA4 | |
| SCHEMBL29434830 | 0.75 | GRM5 (0.40) | GRM5HCAR2CHRNB2CHRNA4 | |
| SCHEMBL1476913 | 0.75 | GRM5 (0.40) | GRM5HCAR2CHRNB2CHRNA4 | |
| SCHEMBL16114950 | 0.74 | CYP11B1 (0.39) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL8486570 | 0.74 | GRM5 (0.47) | GRM5HCAR2CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL19781338 | 0.74 | GRM5 (0.36) | GRM5HCAR2 | |
| SCHEMBL565871 | 0.73 | — | — | |
| SCHEMBL1040544 | 0.73 | — | — | |
| SCHEMBL12805238 | 0.73 | — | — | |
| SCHEMBL1477396 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999055703-A1 | 2-ALKYL-3-(HETERO)ARYL-8-AZABICYCLO[3.2.1]ALKANES AS PESTICIDES | ZENECA LIMITED (GB) | 1999-11-04 | — | — | WO | disclosed |