Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 13/20 | 0.36 |
| ▸ | TYMS | P04818 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488439 | 0.91 | NAMPT (0.43) | NAMPTKMT2AALDH1A1 | |
| SCHEMBL8485127 | 0.89 | EIF4EBP1 (0.34) | KMT2AKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL8488360 | 0.88 | NAMPT (0.40) | NAMPTKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL8488936 | 0.86 | NAMPT (0.38) | NAMPTKMT2A | |
| SCHEMBL9389115 | 0.86 | NAMPT (0.36) | NAMPT | |
| SCHEMBL9389133 | 0.86 | NAMPT (0.36) | NAMPT | |
| SCHEMBL9299312 | 0.84 | TYMS (0.46) | NAMPTTYMS | |
| SCHEMBL9389148 | 0.83 | — | — | |
| SCHEMBL9388293 | 0.82 | NAMPT (0.45) | NAMPTTYMS | |
| SCHEMBL8489290 | 0.82 | KMT2A (0.36) | NAMPTTYMSKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955463-A | ANTITUMOR, ANTIINFLAMMATORY, AND ANTIARTHRITIC AGENTS | ZENECA LIMITED (GB) | 1999-09-21 | — | — | US | disclosed |