SCHEMBL8489507

SCHEMBL8489507

CO[C@]1(C(=O)O)CC(O)[C@@H](NC(C)=O)C([C@H](O)[C@H](O)CO)O1

nearest known ligand 0.74

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NANP Q8TBE9 3/20 0.74
SELL P14151 1/20 0.51
SELP P16109 1/20 0.51
MAG P20916 3/20 0.48
SIGLEC7 Q9Y286 7/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
CD22 P20273 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7066109 1.00 NANP (0.74) NANPSELLSELPMAGSIGLEC7
SCHEMBL28161285 1.00 NANP (0.74) NANPSELLSELPMAGSIGLEC7
SCHEMBL15976325 1.00 NANP (0.74) NANPSELLSELPMAGSIGLEC7
SCHEMBL13125452 1.00 NANP (0.74) NANPSELLSELPMAGSIGLEC7
SCHEMBL2742889 1.00 NANP (0.74) NANPSELLSELPMAGSIGLEC7
SCHEMBL8664558 0.92 NANP (0.64) NANPSELLSELPMAGSIGLEC7
SCHEMBL9253179 0.92 NANP (0.63) NANPSELLSELPMAGSIGLEC7
SCHEMBL14601223 0.91 NANP (0.63) NANPSELLSELPMAGSIGLEC7
SCHEMBL23366254 0.91 NANP (0.74) NANPSELLSELPMAGSIGLEC7
SCHEMBL7263212 0.91 NANP (0.62) NANPSELLSELPMAGSIGLEC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11325936-B2 Sialidase inhibitors and preparation thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-05-10 US disclosed
US-20200190130-A1 SIALIDASE INHIBITORS AND PREPARATION THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-06-18 US disclosed
US-9382284-B2 Neuraminidase inhibitor compounds, compositions and methods for the use thereof in anti-viral treatments THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2016-07-05 US disclosed
US-20150216838-A1 Neuraminidase Inhibitor Compounds, Compositions and Methods for the Use Thereof in Anti-Viral Treatments THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2015-08-06 US disclosed
EP-2454268-B1 2,3-FLUORINATED GLYCOSIDES AS NEURAMINIDASE INHIBITORS AND THEIR USE AS ANTI-VIRALS UNIV BRITISH COLUMBIA (CA) 2014-09-10 EP disclosed
EP-0957107-B1 NOVEL COMPOUNDS HAVING ANTIVIRAL ACTIVITY NISSIN FOOD PRODUCTS LTD (JP) 2004-07-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11325936-B2 Sialidase inhibitors and preparation thereof NEU2, NEU1, NEU3 NANP 31/4885SELL 1097/4885SELP 668/4885
US-20150216838-A1 Neuraminidase Inhibitor Compounds, Compositions and Methods for the Use Thereof in Anti-Viral Treatments NEU1, NEU3, NEU2 NANP 69/4885SELL 1729/4885SELP 666/4885
US-20200190130-A1 SIALIDASE INHIBITORS AND PREPARATION THEREOF NEU2, NEU1, NEU3 NANP 31/4885SELL 1097/4885SELP 668/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.