Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489579 | 1.00 | KDM4E (0.70) | KDM4EMAOBARCA1CA2 | |
| SCHEMBL162076 | 0.95 | KDM4E (0.77) | KDM4EMAOBARCA1CA2 | |
| SCHEMBL162075 | 0.95 | KDM4E (0.77) | KDM4EMAOBARCA1CA2 | |
| SCHEMBL8488847 | 0.88 | KDM4E (0.91) | KDM4EMAOBCA1CA2NFKB1 | |
| SCHEMBL8488850 | 0.88 | KDM4E (0.91) | KDM4EMAOBCA1CA2NFKB1 | |
| SCHEMBL3570479 | 0.84 | MAOB (0.60) | KDM4EMAOBNFKB1GSK3BDRD2 | |
| SCHEMBL3570478 | 0.84 | MAOB (0.60) | KDM4EMAOBNFKB1GSK3BDRD2 | |
| SCHEMBL161792 | 0.83 | GSK3B (0.54) | KDM4EMAOBGSK3BHSD17B10MAPT | |
| SCHEMBL29706697 | 0.83 | GSK3B (0.54) | KDM4EMAOBGSK3BHSD17B10MAPT | |
| SCHEMBL1536574 | 0.83 | KDM4E (1.00) | KDM4EMAOBCA1CA2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856529-A | ADJUSTMENT OF NERVOUS SYSTEM, ENDOCRINE FUNCTION; REPRODUCTION, BODY WEIGHT AND METABOLISM | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-05 | — | — | US | disclosed |