Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | BACE1 | P56817 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.50 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8493392 | 1.00 | TDP1 (0.50) | TDP1CYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL8493401 | 1.00 | TDP1 (0.50) | TDP1CYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL8489791 | 1.00 | TDP1 (0.50) | TDP1CYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL8489900 | 0.94 | MAOB (0.53) | TDP1CYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL8489907 | 0.94 | MAOB (0.53) | TDP1CYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL8492845 | 0.94 | MAOB (0.53) | TDP1CYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL8492838 | 0.94 | MAOB (0.53) | TDP1CYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL8494859 | 0.94 | TDP1 (0.51) | TDP1CYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL8494860 | 0.94 | TDP1 (0.51) | TDP1CYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL8494846 | 0.94 | TDP1 (0.51) | TDP1CYP3A4KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0598117-B1 | BENZOPYRAN DERIVATIVE AND ANTIALLERGIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | DAINIPPON INK & CHEMICALS (JP) | 1999-06-30 | — | — | EP | disclosed |
| US-5428059-A | Benzopyran derivatives and an anti-allergic agent possessing the same as the active ingredient | DAINIPPON INK & CHEMICALS, INC. (JP) | 1995-06-27 | — | — | US | disclosed |
| EP-0598117-A1 | BENZOPYRAN DERIVATIVE AND ANTIALLERGIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1994-05-25 | — | — | EP | disclosed |