Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 4/20 | 0.54 |
| ▸ | PDE2A | O00408 | 1/20 | 0.51 |
| ▸ | NQO1 | P15559 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 4/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | PKLR | P30613 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | GLA | P06280 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8494619 | 0.90 | HSD17B3 (0.55) | HSD17B3PDE2ANQO1ESR1ESR2 | |
| SCHEMBL8496746 | 0.88 | HSD17B3 (0.54) | HSD17B3PDE2ANQO1ESR1ESR2 | |
| SCHEMBL8491466 | 0.87 | KDM4E (0.58) | NQO1MAPTNPSR1RXFP1KDM4E | |
| SCHEMBL8489971 | 0.86 | KDM4E (0.55) | HSD17B3PDE2ANQO1ESR1ESR2 | |
| SCHEMBL8497037 | 0.86 | KDM4E (0.55) | HSD17B3PDE2ANQO1ESR1ESR2 | |
| SCHEMBL8495348 | 0.85 | NQO1 (0.58) | NQO1MAPTKDM4EGLAGAA | |
| SCHEMBL15950101 | 0.84 | HSD17B3 (0.65) | HSD17B3PDE2AESR1ESR2MAPT | |
| SCHEMBL8493212 | 0.83 | KDM4E (0.61) | HSD17B3PDE2ANQO1ESR1ESR2 | |
| SCHEMBL8494299 | 0.82 | KDM4E (0.54) | NQO1MAPTNPSR1KDM4EGLA | |
| SCHEMBL8492707 | 0.82 | AKR1B1 (0.48) | HSD17B3PDE2ANQO1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0598117-B1 | BENZOPYRAN DERIVATIVE AND ANTIALLERGIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | DAINIPPON INK & CHEMICALS (JP) | 1999-06-30 | — | — | EP | disclosed |
| US-5428059-A | Benzopyran derivatives and an anti-allergic agent possessing the same as the active ingredient | DAINIPPON INK & CHEMICALS, INC. (JP) | 1995-06-27 | — | — | US | disclosed |
| EP-0598117-A1 | BENZOPYRAN DERIVATIVE AND ANTIALLERGIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1994-05-25 | — | — | EP | disclosed |