Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 8/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8494395 | 0.92 | KDM4E (0.59) | NQO1KDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL8492386 | 0.89 | KDM4E (0.56) | NQO1KDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL8494601 | 0.89 | NQO1 (0.61) | NQO1KDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL8493442 | 0.89 | KDM4E (0.60) | NQO1KDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL8490823 | 0.87 | KDM4E (0.59) | NQO1KDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL8085834 | 0.87 | NQO1 (0.65) | NQO1KDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL8492717 | 0.87 | KDM4E (0.56) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL8496761 | 0.86 | KDM4E (0.57) | NQO1KDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL8492430 | 0.86 | KDM4E (0.47) | NQO1KDM4EALDH1A1MAPTNPC1 | |
| SCHEMBL8490883 | 0.85 | HSD17B3 (0.54) | NQO1KDM4EALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0598117-B1 | BENZOPYRAN DERIVATIVE AND ANTIALLERGIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | DAINIPPON INK & CHEMICALS (JP) | 1999-06-30 | — | — | EP | disclosed |
| US-5428059-A | Benzopyran derivatives and an anti-allergic agent possessing the same as the active ingredient | DAINIPPON INK & CHEMICALS, INC. (JP) | 1995-06-27 | — | — | US | disclosed |
| EP-0598117-A1 | BENZOPYRAN DERIVATIVE AND ANTIALLERGIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1994-05-25 | — | — | EP | disclosed |