Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | GLA | P06280 | 6/20 | 0.61 |
| ▸ | GAA | P10253 | 5/20 | 0.61 |
| ▸ | CASP1 | P29466 | 3/20 | 0.56 |
| ▸ | CASP7 | P55210 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | NQO1 | P15559 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GAPDH | P04406 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8494030 | 0.88 | KDM4E (0.58) | KDM4EALDH1A1GLAGAACASP1 | |
| SCHEMBL8491466 | 0.88 | KDM4E (0.58) | KDM4EALDH1A1GLAGAACASP1 | |
| SCHEMBL8496747 | 0.86 | KDM4E (0.56) | KDM4EALDH1A1GLAGAACASP1 | |
| SCHEMBL8081672 | 0.86 | KDM4E (0.56) | KDM4EALDH1A1GLAGAACASP1 | |
| SCHEMBL8492659 | 0.85 | KDM4E (0.62) | KDM4EALDH1A1GLAGAACASP1 | |
| SCHEMBL8492717 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1GLAGAACASP1 | |
| SCHEMBL8492972 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1GLAGAACASP1 | |
| SCHEMBL6276172 | 0.83 | NQO1 (0.73) | KDM4EALDH1A1GAACASP1CASP7 | |
| SCHEMBL8496602 | 0.82 | KDM4E (0.61) | KDM4EALDH1A1GLAGAACASP1 | |
| SCHEMBL26780129 | 0.81 | PDE2A (0.65) | KDM4EALDH1A1GLAGAACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0598117-B1 | BENZOPYRAN DERIVATIVE AND ANTIALLERGIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | DAINIPPON INK & CHEMICALS (JP) | 1999-06-30 | — | — | EP | disclosed |
| US-5428059-A | Benzopyran derivatives and an anti-allergic agent possessing the same as the active ingredient | DAINIPPON INK & CHEMICALS, INC. (JP) | 1995-06-27 | — | — | US | disclosed |
| EP-0598117-A1 | BENZOPYRAN DERIVATIVE AND ANTIALLERGIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1994-05-25 | — | — | EP | disclosed |