Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2376514 | 0.84 | TDP1 (0.50) | TDP1MAPK1HSD17B10 | |
| SCHEMBL2241100 | 0.82 | TDP1 (0.48) | TDP1MAPK1HSD17B10 | |
| SCHEMBL8496542 | 0.82 | MAPK1 (0.43) | TDP1MAPK1HSD17B10LMNA | |
| SCHEMBL11573684 | 0.79 | TDP1 (0.46) | TDP1MAPK1HSD17B10 | |
| SCHEMBL43392 | 0.77 | TDP1 (0.71) | TDP1MAPK1HSD17B10LMNA | |
| SCHEMBL11572554 | 0.76 | TDP1 (0.47) | TDP1HSD17B10 | |
| SCHEMBL16072 | 0.75 | TDP1 (0.61) | TDP1MAPK1HSD17B10LMNA | |
| SCHEMBL17504736 | 0.75 | TDP1 (0.68) | TDP1MAPK1HSD17B10LMNA | |
| SCHEMBL250892 | 0.75 | TDP1 (0.68) | TDP1MAPK1HSD17B10LMNA | |
| SCHEMBL535994 | 0.75 | TDP1 (0.56) | TDP1MAPK1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981612-A | Production of flameproofed, rigid, isocyanate-based foams | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |
| EP-0719807-B1 | Process for the preparation of flame-proofed rigid foams based on isocyanate | BASF SCHWARZHEIDE GMBH (DE) | 1999-11-03 | — | — | EP | disclosed |
| EP-0908464-A1 | Process for the preparation of hydroxyphosphonates and their use as flame retardants in polymers | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-14 | — | — | EP | disclosed |
| EP-0719807-A2 | Process for the preparation of flame-proofed rigid foams based on isocyanate | BASF SCHWARZHEIDE GmbH (DE) | 1996-07-03 | — | — | EP | disclosed |