Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207611 | 0.88 | CA1 (0.37) | CA12CA1CA2CA9 | |
| SCHEMBL7206852 | 0.88 | CA12 (0.37) | CA12CA1CA2CA9 | |
| SCHEMBL7211026 | 0.82 | CHRM2 (0.38) | CA12CA1CA2CA9 | |
| SCHEMBL7211202 | 0.81 | CA12 (0.38) | CA12CA1CA2CA9STS | |
| SCHEMBL7211259 | 0.81 | CHRM3 (0.38) | — | |
| SCHEMBL7212811 | 0.80 | CHRM3 (0.39) | — | |
| SCHEMBL7211822 | 0.80 | STS (0.40) | CA12CA1CA2CA9CES2 | |
| SCHEMBL7207511 | 0.78 | STS (0.48) | CA12CA1CA2CA9STS | |
| SCHEMBL7206838 | 0.78 | CA1 (0.37) | CA12CA1CA2CA9STS | |
| SCHEMBL8496123 | 0.77 | CA1 (0.38) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0698010-B1 | N-ACYL SULFAMIC ACID ESTERS (OR THIOESTERS), N-ACYL SULFONAMIDES, AND N-SULFONYL CARBAMIC ACID ESTERS (OR THIOESTERS) AS HYPERCHOLESTEROLEMIC AGENTS | WARNER LAMBERT CO (US) | 1999-04-14 | — | — | EP | disclosed |
| WO-1994026702-A1 | N-ACYL SULFAMIC ACID ESTERS (OR THIOESTERS), N-ACYL SULFONAMIDES, AND N-SULFONYL CARBAMIC ACID ESTERS (OR THIOESTERS) AS HYPERCHOLESTEROLEMIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1994-11-24 | — | — | WO | disclosed |