Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8497443 | 1.00 | TAAR1 (0.48) | TAAR1MAOBLMNAIDO1LOXL2 | |
| SCHEMBL8498563 | 1.00 | TAAR1 (0.48) | TAAR1MAOBLMNAIDO1LOXL2 | |
| SCHEMBL8497299 | 1.00 | TAAR1 (0.48) | TAAR1MAOBLMNAIDO1LOXL2 | |
| SCHEMBL8499777 | 1.00 | TAAR1 (0.48) | TAAR1MAOBLMNAIDO1LOXL2 | |
| SCHEMBL8499020 | 1.00 | TAAR1 (0.48) | TAAR1MAOBLMNAIDO1LOXL2 | |
| SCHEMBL1047917 | 1.00 | TAAR1 (0.48) | TAAR1MAOBLMNAIDO1LOXL2 | |
| SCHEMBL1045945 | 1.00 | TAAR1 (0.48) | TAAR1MAOBLMNAIDO1LOXL2 | |
| SCHEMBL8498682 | 1.00 | TAAR1 (0.48) | TAAR1MAOBLMNAIDO1LOXL2 | |
| SCHEMBL8495738 | 1.00 | TAAR1 (0.48) | TAAR1MAOBLMNAIDO1LOXL2 | |
| SCHEMBL1287203 | 0.98 | TAAR1 (0.50) | TAAR1MAOBLMNAIDO1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |