SCHEMBL8498592 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	CYP11B1	P15538	3/20	0.40

▸	CYP11B2	P19099	3/20	0.40

▸	FNTA	P49354	10/20	0.40

▸	FNTB	P49356	10/20	0.40

▸	PGGT1B	P53609	7/20	0.38

▸	KDM4E	B2RXH2	1/20	0.38

▸	POLB	P06746	1/20	0.38

▸	TSHR	P16473	1/20	0.38

▸	SMN1; SMN2	Q16637	1/20	0.38

▸	HSD17B10	Q99714	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8498589	1.00	CYP11B1 (0.40)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8486401	0.93	CYP11B1 (0.43)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8486406	0.93	CYP11B1 (0.43)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8498744	0.93	CYP11B1 (0.39)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8498742	0.93	CYP11B1 (0.39)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8489464	0.91	FNTA (0.39)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8489468	0.91	FNTA (0.39)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8489925	0.89	FNTA (0.38)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8501590	0.89	CYP11B1 (0.41)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8498038	0.89	FNTA (0.39)	CYP11B1CYP11B2FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1999012912-A1	THIOUREA DERIVATIVES OR NON-TOXIC SALTS THEREOF FOR INHIBITNG RAS-TRANSFORMED CELL GROWTH	YUHAN CORPORATION (KR)	1999-03-18	—	—	WO	disclosed