SCHEMBL8498779

SCHEMBL8498779

O=C1CCCCCCC1Cl

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.52
CA1 P00915 4/20 0.48
CA2 P00918 4/20 0.48
CA4 P22748 3/20 0.48
TRIM24 O15164 2/20 0.36
TRIM33 Q9UPN9 2/20 0.36
ALDH1A1 P00352 1/20 0.36
MCL1 Q07820 1/20 0.35
CA6 P23280 2/20 0.35
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
TLR4 O00206 1/20 0.33
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33
MT-CO2 P00403 1/20 0.32
ALOX5 P09917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5163241 1.00 KMT2A (0.52) KMT2ACA1CA2CA4TRIM24
SCHEMBL11476922 1.00 KMT2A (0.52) KMT2ACA1CA2CA4TRIM24
SCHEMBL11459172 1.00 KMT2A (0.52) KMT2ACA1CA2CA4TRIM24
SCHEMBL11476526 1.00 KMT2A (0.52) KMT2ACA1CA2CA4TRIM24
SCHEMBL2193685 1.00
SCHEMBL186361 0.97
SCHEMBL16808734 0.97
SCHEMBL15171236 0.97
Cyclohexanone SCHEMBL11188977 0.93 TRIM24 (0.50) KMT2ACA1CA2CA4TRIM24
SCHEMBL172692 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117964626-A Method for preparing indole [3,2-a ] carbazole alkaloid by taking 2, 3' -biindole as raw material 重庆医科大学 2024-05-03 CN disclosed
CN-113861137-B Method for synthesizing furan compound by one-step reaction of ketone and alpha chloroketone 重庆医科大学 2023-08-15 CN disclosed
CN-113861137-A Method for synthesizing furan compound by one-step reaction of ketone and alpha chloroketone 重庆医科大学 2021-12-31 CN disclosed
CN-1155624-C Cyclic ketone peroxides as polymerization initiators ��˹��ŵ�� 2004-06-30 CN disclosed
EP-0813550-B1 CYCLIC KETONE PEROXIDES AS POLYMER INITIATORS AKZO NOBEL NV (NL) 1999-11-24 EP disclosed
US-5907022-A Cyclic ketone peroxides as polymer initiators AKZO NOBEL NV (NL) 1999-05-25 US disclosed
CN-1181088-A Cyclic ketone peroxides as polymerization initiators AKZO NOBEL NV (NL) 1998-05-06 CN disclosed
EP-0813550-A1 CYCLIC KETONE PEROXIDES AS POLYMER INITIATORS Akzo Nobel N.V. (NL) 1997-12-29 EP disclosed
WO-1996027620-A1 CYCLIC KETONE PEROXIDES AS POLYMER INITIATORS AKZO NOBEL N.V. (NL) 1996-09-12 WO disclosed
US-5476944-A Inhibitors or stimulators of superoxide generation; may also inhibit cyclooxygenase and/or 5-lipoxygenase; useful in therapeutic or prophylactic treatment of disease conditions G. D. SEARLE & CO. (US) 1995-12-19 US disclosed
EP-0613463-A1 DERIVATIVES OF CYCLIC PHENOLIC THIOETHERS AS INHIBITORS OR STIMULATORS OF SUPEROXIDE GENERATION G.D. SEARLE & CO. (US) 1994-09-07 EP disclosed
WO-1993010087-A1 DERIVATIVES OF CYCLIC PHENOLIC THIOETHERS AS INHIBITORS OR STIMULATORS OF SUPEROXIDE GENERATION G.D. SEARLE & CO. (US) 1993-05-27 WO disclosed
US-4240983-A HALOGENATION BAYER AKTIENGESELLSCHAFT (DE) 1980-12-23 US disclosed
US-4153606-A Process for the production of thiazoline-(3) compounds DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1979-05-08 US disclosed
US-3954981-A Triazolocycloalkylhydrothiadiazine derivatives RICHARDSON-MERRELL INC. (US) 1976-05-04 US disclosed
US-3954984-A ANTISECRETRETORY AGENTS, CENTRAL NERVOUS SYSTEM DEPRESSANTS RICHARDSON-MERRELL INC. (US) 1976-05-04 US disclosed