Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 11/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6962351 | 1.00 | GRIN1 (0.39) | GRIN1GRIN2BSRCHPGDPKM | |
| SCHEMBL6973265 | 0.93 | GRIN1 (0.39) | GRIN1GRIN2BSRCHPGDPKM | |
| SCHEMBL6973263 | 0.93 | GRIN1 (0.39) | GRIN1GRIN2BSRCHPGDPKM | |
| SCHEMBL6970763 | 0.89 | SRC (0.34) | GRIN1GRIN2BSRCPKMALOX5AP | |
| SCHEMBL6970767 | 0.89 | SRC (0.34) | GRIN1GRIN2BSRCPKMALOX5AP | |
| SCHEMBL8099986 | 0.89 | ALOX5AP (0.35) | SRCHPGDGAAALOX5AP | |
| SCHEMBL6960954 | 0.89 | KCNK13 (0.30) | GRIN1GRIN2B | |
| SCHEMBL6960949 | 0.89 | KCNK13 (0.30) | GRIN1GRIN2B | |
| SCHEMBL8099988 | 0.89 | ALOX5AP (0.35) | SRCHPGDGAAALOX5AP | |
| SCHEMBL6967171 | 0.88 | GRIN1 (0.41) | GRIN1GRIN2BSRCHPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |