Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499243 | 1.00 | AR (0.54) | ARSRD5A2KCNH2 | |
| SCHEMBL8902473 | 0.89 | AR (0.56) | ARSRD5A2KCNH2 | |
| SCHEMBL8499208 | 0.85 | AR (0.52) | ARSRD5A2KCNH2 | |
| SCHEMBL8499204 | 0.85 | AR (0.52) | ARSRD5A2KCNH2 | |
| SCHEMBL8495705 | 0.85 | — | — | |
| SCHEMBL8495710 | 0.85 | — | — | |
| SCHEMBL8495762 | 0.84 | AR (0.53) | ARSRD5A2KCNH2 | |
| SCHEMBL8495760 | 0.84 | AR (0.53) | ARSRD5A2KCNH2 | |
| SCHEMBL8496657 | 0.84 | AR (0.63) | ARSRD5A2KCNH2 | |
| SCHEMBL8496405 | 0.84 | AR (0.56) | ARSRD5A2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649431-B1 | 17-AMINO SUBSTITUTED 4-AZASTEROID 5-ALPHA-REDUCTASE INHIBITORS | MERCK & CO INC (US) | 1999-08-11 | — | — | EP | claimed |
| US-5639741-A | STEROIDS TREATING SKIN DISORDERS | MERCK & CO., INC. (US) | 1997-06-17 | — | — | US | claimed |