Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.60 |
| ▸ | CA2 | P00918 | 2/20 | 0.60 |
| ▸ | CA4 | P22748 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.57 |
| ▸ | DPP4 | P27487 | 5/20 | 0.55 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.53 |
| ▸ | REN | P00797 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28045116 | 0.88 | CA1 (0.62) | CA1CA2CA4CA9SLC6A4 | |
| SCHEMBL590923 | 0.88 | CA1 (0.62) | CA1CA2CA4CA9SLC6A4 | |
| SCHEMBL4584365 | 0.86 | CA1 (0.63) | CA1CA2CA4CA9SLC6A4 | |
| SCHEMBL3507642 | 0.82 | DPP4 (0.57) | CA1CA2CA4CA9SLC6A4 | |
| SCHEMBL3507638 | 0.82 | DPP4 (0.57) | CA1CA2CA4CA9SLC6A4 | |
| SCHEMBL9988384 | 0.82 | DPP4 (0.57) | CA1CA2CA4CA9SLC6A4 | |
| SCHEMBL1619035 | 0.82 | CA1 (0.57) | CA1CA2CA4CA9SLC6A4 | |
| SCHEMBL1619197 | 0.81 | CA1 (0.56) | CA1CA2CA4CA9SLC6A4 | |
| SCHEMBL21594461 | 0.81 | CA1 (0.56) | CA1CA2CA4CA9SLC6A4 | |
| SCHEMBL21590395 | 0.81 | CA1 (0.56) | CA1CA2CA4CA9SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552417-B1 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-07-07 | — | — | EP | disclosed |
| EP-0528312-B1 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-07-16 | — | — | EP | disclosed |