Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 13/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8496515 | 0.84 | CAPN1 (0.46) | CAPN1MTNR1A | |
| SCHEMBL8499695 | 0.83 | CAPN1 (0.43) | CAPN1MTNR1AALDH1A1KDM4E | |
| SCHEMBL8498085 | 0.71 | CAPN1 (0.62) | CAPN1 | |
| SCHEMBL8499527 | 0.68 | CAPN1 (0.57) | CAPN1ALDH1A1KDM4E | |
| SCHEMBL8499658 | 0.67 | CAPN1 (0.53) | CAPN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8497642 | 0.65 | CAPN1 (0.55) | CAPN1 | |
| SCHEMBL8494762 | 0.63 | CAPN1 (0.58) | CAPN1 | |
| SCHEMBL8497487 | 0.63 | CAPN1 (0.58) | CAPN1 | |
| SCHEMBL8500284 | 0.62 | CAPN1 (0.54) | CAPN1 | |
| SCHEMBL7355411 | 0.61 | CAPN1 (0.62) | CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952328-A | MAY BE USED TO ALLEVIATE, MEDIATE, REDUCE AND/OR PREVENT DISORDERS WHICH ARE ASSOCIATED WITH ABNORMAL AND/OR ABERRANT ACTIVITY OF CYSTEINE PROTEASES AND/OR SERINE PROTEASES | CEPHALON, INC. (US) | 1999-09-14 | — | — | US | disclosed |