Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.62 |
| ▸ | PPARG | P37231 | 3/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.58 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15016678 | 0.98 | PPARA (0.59) | PPARAPPARGCNR1CNR2GGPS1 | |
| SCHEMBL3025797 | 0.95 | PPARA (0.64) | PPARAPPARGCNR1CNR2GGPS1 | |
| SCHEMBL4568893 | 0.94 | PPARA (0.58) | PPARAPPARGCNR1CNR2GGPS1 | |
| SCHEMBL27783742 | 0.92 | PPARA (0.59) | PPARAPPARGCNR1CNR2GGPS1 | |
| SCHEMBL4568872 | 0.92 | PPARA (0.56) | PPARAPPARGCNR1CNR2GGPS1 | |
| SCHEMBL6257571 | 0.91 | PPARA (0.66) | PPARAPPARGCNR1CNR2GGPS1 | |
| SCHEMBL11320800 | 0.91 | PPARA (0.66) | PPARAPPARGCNR1CNR2GGPS1 | |
| SCHEMBL7215970 | 0.91 | PPARA (0.54) | PPARAPPARGCNR1CNR2GGPS1 | |
| SCHEMBL4568880 | 0.91 | PPARA (0.57) | PPARAPPARGCNR1CNR2GGPS1 | |
| SCHEMBL17509796 | 0.91 | PPARA (0.68) | PPARAPPARGCNR1CNR2GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952316-A | FOR TREATING AUTOIMMUNE DISEASES, E.G., RHEUMATIOD ARTHRITIS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0627406-B1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5719176-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5604229-A | 2-amino-1,3-propanediol compound and immunosuppressant | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-02-18 | — | — | US | disclosed |
| EP-0627406-A1 | 2-AMINO-1,3-PROPANEDIOL COMPOUND AND IMMUNOSUPPRESSANT | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |