Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8500047 | 1.00 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1PTGER1PTGER4PTGER3 | |
| SCHEMBL9691037 | 0.88 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1 | |
| SCHEMBL9691042 | 0.88 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1 | |
| SCHEMBL8500058 | 0.86 | — | — | |
| SCHEMBL8500060 | 0.86 | — | — | |
| SCHEMBL8500092 | 0.83 | — | — | |
| SCHEMBL8500094 | 0.83 | — | — | |
| SCHEMBL8500089 | 0.82 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1PTGER1PTGER4PTGER3 | |
| SCHEMBL8500086 | 0.82 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1PTGER1PTGER4PTGER3 | |
| SCHEMBL9691074 | 0.81 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856322-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, CARDIOVASCULAR DISORDERS | MERCK FROSST CANADA, INC. (CA) | 1999-01-05 | — | — | US | disclosed |
| US-5565473-A | USEFUL AS ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND CYTOPROTECTIVE AGENTS; MONTELUKAST AND ITS SODIUM SALT | MERCK FROSST CANADA, INC. (CA) | 1996-10-15 | — | — | US | disclosed |
| US-5270324-A | Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists | MERCK FROSST CANADA, INC. (CA) | 1993-12-14 | — | — | US | disclosed |