Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.57 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.57 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.57 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.57 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.57 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.57 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.57 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.57 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.54 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.54 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.54 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501451 | 0.86 | GRIN1 (0.58) | GRIN1MEN1CYP2C9GRIK1GRIA1 | |
| SCHEMBL8499347 | 0.85 | GRIN1 (0.60) | GRIN1MEN1CYP2C9GRIK1GRIA1 | |
| SCHEMBL8501801 | 0.80 | GRIN1 (0.51) | GRIN1MEN1CYP2C9GRIK1GRIA1 | |
| SCHEMBL7787746 | 0.79 | GRIN1 (0.64) | GRIN1MEN1CYP2C9GRIK1GRIA1 | |
| SCHEMBL8498392 | 0.79 | GRIN1 (0.60) | GRIN1MEN1CYP2C9GRIK1GRIA1 | |
| SCHEMBL8500332 | 0.79 | GRIN1 (0.60) | GRIN1MEN1CYP2C9GRIK1GRIA1 | |
| SCHEMBL8085876 | 0.78 | GRIN1 (0.61) | GRIN1MEN1CYP2C9GRIK1GRIA1 | |
| SCHEMBL8085960 | 0.78 | GRIN1 (0.56) | GRIN1MEN1CYP2C9GRIK1GRIA1 | |
| SCHEMBL8500945 | 0.78 | GRIN1 (0.61) | GRIN1 | |
| SCHEMBL12643355 | 0.77 | GRIN1 (0.69) | GRIN1MEN1CYP2C9GRIK1GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934326-A1 | SUBSTITUTED AMINOALKANE PHOSPHONIC ACIDS | Novartis AG (CH) | 1999-08-11 | — | — | EP | claimed |
| WO-1998017672-A1 | SUBSTITUTED AMINOALKANE PHOSPHONIC ACIDS | NOVARTIS AG (CH) | 1998-04-30 | — | — | WO | claimed |