Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 8/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8498189 | 0.85 | GRIN1 (0.55) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8499247 | 0.84 | GRIN1 (0.53) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL5973955 | 0.81 | GRIN1 (0.61) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| Phosphonic Acid SCHEMBL8193513 | 0.81 | GRIN1 (0.50) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8500917 | 0.75 | GRIN1 (0.56) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL8500955 | 0.74 | GRIN1 (0.48) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| Phosphonic Acid SCHEMBL27504235 | 0.73 | GRIN1 (0.60) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| SCHEMBL5973604 | 0.72 | GRIN1 (0.62) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| Bromide SCHEMBL5973853 | 0.71 | GRIN1 (0.61) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B | |
| Phosphonic Acid SCHEMBL8193317 | 0.69 | GRIN1 (0.46) | GRIN1GRIN2DGRIN3BGRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934326-A1 | SUBSTITUTED AMINOALKANE PHOSPHONIC ACIDS | Novartis AG (CH) | 1999-08-11 | — | — | EP | claimed |
| WO-1998017672-A1 | SUBSTITUTED AMINOALKANE PHOSPHONIC ACIDS | NOVARTIS AG (CH) | 1998-04-30 | — | — | WO | claimed |