SCHEMBL8500987

SCHEMBL8500987

CCCNC1CC(C)(C)CC(C)(CN)C1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
PBK Q96KB5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8499396 0.90 TSHR (0.33) TSHRPBK
SCHEMBL8502554 0.86 TSHR (0.36) TSHRPBK
SCHEMBL9812319 0.85 TSHR (0.37) TSHRPBK
SCHEMBL16295954 0.82 SQLE (0.37) TSHRPBK
SCHEMBL16295766 0.82 SQLE (0.37) TSHRPBK
SCHEMBL15373389 0.81 TSHR (0.39) TSHRPBK
SCHEMBL16295541 0.80 TSHR (0.39) TSHRPBK
SCHEMBL1832852 0.78 TSHR (0.38) TSHRPBK
SCHEMBL8499269 0.78 TSHR (0.38) TSHRPBK
SCHEMBL4552065 0.78 TSHR (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0938494-A1 INHIBITORS OF PROTEIN FARNESYL TRANSFERASE WARNER-LAMBERT COMPANY (US) 1999-09-01 EP disclosed
WO-1997044350-A1 INHIBITORS OF PROTEIN FARNESYL TRANSFERASE WARNER-LAMBERT COMPANY (US) 1997-11-27 WO disclosed
US-5554703-A Nitrogenous multiacrylic monomers, their preparation and their application to the obtention of new polymers CRAY VALLEY S.A. (FR) 1996-09-10 US disclosed
EP-0572651-B1 NITROGENOUS MULTIACRYLIC MONOMERS, PREPARATION AND APPLICATION THEREOF IN PRODUCING NOVEL POLYMERS CRAY VALLEY SA (FR) 1996-08-21 EP disclosed
WO-1995000598-A1 METHOD FOR PRODUCING A STRUCTURAL ADHESIVE AND METHOD FOR ASSEMBLING SAME CRAY VALLEY S.A. (FR) 1995-01-05 WO disclosed
EP-0572651-A1 NITROGENOUS MULTIACRYLIC MONOMERS, PREPARATION AND APPLICATION THEREOF IN PRODUCING NOVEL POLYMERS. CRAY VALLEY SA (FR) 1993-12-08 EP disclosed
WO-1993013050-A1 NITROGENOUS MULTIACRYLIC MONOMERS, PREPARATION AND APPLICATION THEREOF IN PRODUCING NOVEL POLYMERS CRAY VALLEY S.A. (FR) 1993-07-08 WO disclosed