Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 10/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8505447 | 0.92 | FDFT1 (0.43) | FDFT1 | |
| SCHEMBL8502290 | 0.85 | FDFT1 (0.42) | FDFT1 | |
| SCHEMBL8504660 | 0.84 | FDFT1 (0.49) | FDFT1 | |
| SCHEMBL6961886 | 0.84 | FDFT1 (0.46) | FDFT1 | |
| SCHEMBL8504873 | 0.79 | FDFT1 (0.52) | FDFT1 | |
| SCHEMBL8504340 | 0.79 | FDFT1 (0.47) | FDFT1 | |
| SCHEMBL8503929 | 0.78 | FDFT1 (0.41) | FDFT1 | |
| SCHEMBL8503972 | 0.78 | FDFT1 (0.41) | FDFT1 | |
| SCHEMBL4105096 | 0.78 | FDFT1 (0.64) | FDFT1 | |
| SCHEMBL9057751 | 0.78 | FDFT1 (0.64) | FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885979-A | SQUALENE SYNTHETASE INHIBITOR TREATING OR PREVENTING HYPERLIPIDEMIA | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-23 | — | — | US | disclosed |
| US-5726306-A | INHIBITORS OF SQUALENE SYNTHETASE AND FUNGAL GROWTH; USEFUL IN TREATING AND PREVENTING HYPERLIPIDEMIA | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-10 | — | — | US | disclosed |