SCHEMBL8501176 — predicted protein targets

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	CYP11B1	P15538	4/20	0.40

▸	CYP11B2	P19099	4/20	0.40

▸	FNTA	P49354	13/20	0.39

▸	FNTB	P49356	13/20	0.39

▸	PGGT1B	P53609	7/20	0.39

▸	KCNH2	Q12809	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8497333	0.93	FNTA (0.41)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8480741	0.93	FNTA (0.42)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8480737	0.93	FNTA (0.42)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8486074	0.93	CYP11B1 (0.41)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8501664	0.93	CYP11B1 (0.42)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8499040	0.91	FNTA (0.41)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8489869	0.91	CYP11B1 (0.41)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8664357	0.91	CYP11B1 (0.41)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8498220	0.90	CYP11B1 (0.42)	CYP11B1CYP11B2FNTAFNTBPGGT1B
SCHEMBL8486598	0.90	FNTA (0.39)	CYP11B1CYP11B2FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-1999012912-A1	THIOUREA DERIVATIVES OR NON-TOXIC SALTS THEREOF FOR INHIBITNG RAS-TRANSFORMED CELL GROWTH	YUHAN CORPORATION (KR)	1999-03-18	—	—	WO	disclosed