Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 13/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6957317 | 0.89 | FDFT1 (0.50) | FDFT1 | |
| SCHEMBL6957323 | 0.89 | FDFT1 (0.50) | FDFT1 | |
| SCHEMBL6957312 | 0.89 | FDFT1 (0.50) | FDFT1 | |
| Acetic Acid SCHEMBL6962426 | 0.88 | FDFT1 (0.42) | FDFT1 | |
| SCHEMBL8504873 | 0.85 | FDFT1 (0.52) | FDFT1 | |
| SCHEMBL6962424 | 0.83 | FDFT1 (0.54) | FDFT1 | |
| SCHEMBL6962418 | 0.83 | FDFT1 (0.54) | FDFT1 | |
| SCHEMBL6951630 | 0.82 | FDFT1 (0.39) | FDFT1 | |
| SCHEMBL6957042 | 0.82 | FDFT1 (0.38) | FDFT1 | |
| SCHEMBL6957046 | 0.82 | FDFT1 (0.38) | FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885979-A | SQUALENE SYNTHETASE INHIBITOR TREATING OR PREVENTING HYPERLIPIDEMIA | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-03-23 | — | — | US | disclosed |
| US-5726306-A | INHIBITORS OF SQUALENE SYNTHETASE AND FUNGAL GROWTH; USEFUL IN TREATING AND PREVENTING HYPERLIPIDEMIA | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-10 | — | — | US | disclosed |