Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631391 | 0.91 | EDNRA (0.84) | EDNRAEDNRB | |
| SCHEMBL8503983 | 0.86 | EDNRA (0.79) | EDNRAEDNRB | |
| SCHEMBL4630626 | 0.86 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL4632019 | 0.85 | EDNRA (0.73) | EDNRAEDNRB | |
| SCHEMBL4630670 | 0.84 | EDNRA (0.87) | EDNRAEDNRB | |
| SCHEMBL5212401 | 0.84 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6151644 | 0.84 | EDNRA (0.81) | EDNRAEDNRB | |
| SCHEMBL6588138 | 0.83 | EDNRA (0.80) | EDNRAEDNRB | |
| SCHEMBL4630657 | 0.83 | EDNRA (0.73) | EDNRAEDNRB | |
| SCHEMBL4631499 | 0.83 | EDNRA (0.78) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962490-A | Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1999-10-05 | — | — | US | claimed |
| US-5962490-A | Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1999-10-05 | — | — | US | disclosed |