Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.51 |
| ▸ | F10 | P00742 | 3/20 | 0.51 |
| ▸ | PLAT | P00750 | 2/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.51 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501786 | 0.95 | F2 (0.49) | F2F10PLATPRSS1PRSS2 | |
| SCHEMBL5772427 | 0.81 | F2 (0.38) | F2F10PLATPRSS1PRSS2 | |
| SCHEMBL8292318 | 0.75 | F2 (0.51) | F2F10PLATPRSS1PRSS2 | |
| SCHEMBL8292311 | 0.74 | F2 (0.59) | F2F10PLATPRSS1PRSS2 | |
| SCHEMBL14534430 | 0.72 | F2 (0.48) | F2F10PLATPRSS1PRSS2 | |
| SCHEMBL6990304 | 0.69 | POLB (0.66) | F2F10PLATPRSS1PRSS2 | |
| SCHEMBL29813025 | 0.69 | POLB (0.66) | F2F10PLATPRSS1PRSS2 | |
| SCHEMBL20828207 | 0.69 | POLB (0.66) | F2F10PLATPRSS1PRSS2 | |
| SCHEMBL8293315 | 0.69 | F2 (0.53) | F2F10PLATPRSS1PRSS2 | |
| SCHEMBL11478700 | 0.68 | POLB (0.64) | F2F10PLATPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1674464-A1 | Novel thrombin inhibitors | Santhera Pharmaceuticals (Schweiz) GmbH (CH) | 2006-06-28 | — | — | EP | disclosed |