Ether

Ether

SCHEMBL8501725

CCCCCOCC(O)CO.CCOCC

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.85
HTT P42858 2/20 0.59
LPAR5 Q9H1C0 4/20 0.51
PLA2G2C Q5R387 1/20 0.50
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C19 P33261 1/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
SPHK1 Q9NYA1 1/20 0.46
KDM4E B2RXH2 1/20 0.46
DUSP3 P51452 1/20 0.46
LMNA P02545 1/20 0.46
THRB P10828 1/20 0.44
MAPT P10636 1/20 0.44
HSD17B10 Q99714 1/20 0.42
LPAR1 Q92633 4/20 0.40
LPAR2 Q9HBW0 4/20 0.40
LPAR3 Q9UBY5 4/20 0.40
LPAR6 P43657 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL2015031 0.98 USP2 (0.89) USP2HTTLPAR5PLA2G2CCYP1A2
Ether SCHEMBL2390477 0.98 USP2 (0.89) USP2HTTLPAR5PLA2G2CCYP1A2
Ether SCHEMBL93806 0.98 USP2 (0.89) USP2HTTLPAR5PLA2G2CCYP1A2
Batilol SCHEMBL940982 0.98 USP2 (0.89) USP2HTTLPAR5PLA2G2CCYP1A2
Ether SCHEMBL6428915 0.98 USP2 (0.89) USP2HTTLPAR5PLA2G2CCYP1A2
Ether SCHEMBL8502252 0.98 USP2 (0.89) USP2HTTLPAR5PLA2G2CCYP1A2
Ether SCHEMBL8501744 0.98 USP2 (0.89) USP2HTTLPAR5PLA2G2CCYP1A2
Ether SCHEMBL6805057 0.98 USP2 (0.89) USP2HTTLPAR5PLA2G2CCYP1A2
Ether SCHEMBL3811088 0.98 USP2 (0.89) USP2HTTLPAR5PLA2G2CCYP1A2
SCHEMBL11158 0.94 USP2 (0.96) USP2HTTLPAR5PLA2G2CCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5916884-A CYTOTOXIC THERAPEUTIC COMPOUND; ANTITUMOR AGENT MAX-PLANCK-GESELLSCHAFT ZUR FOEDERUNG DER WISSENSCHAFTEN (DE) 1999-06-29 US claimed