Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.62 |
| ▸ | MASP2 | O00187 | 1/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7022075 | 0.94 | F2 (0.65) | F2PRSS1MASP2PRSS2PRSS3 | |
| SCHEMBL7018727 | 0.92 | F2 (0.62) | F2PRSS1MASP2PRSS2PRSS3 | |
| SCHEMBL7023265 | 0.90 | F2 (0.60) | F2PRSS1MASP2PRSS2PRSS3 | |
| SCHEMBL7025115 | 0.89 | F2 (0.58) | F2PRSS1MASP2PRSS2PRSS3 | |
| SCHEMBL7017898 | 0.89 | F2 (0.58) | F2PRSS1MASP2PRSS2PRSS3 | |
| SCHEMBL7027525 | 0.89 | F2 (0.60) | F2PRSS1MASP2PRSS2PRSS3 | |
| SCHEMBL7021532 | 0.88 | F2 (0.60) | F2PRSS1MASP2PRSS2PRSS3 | |
| SCHEMBL8489300 | 0.88 | F2 (0.59) | F2PRSS1MASP2PRSS2PRSS3 | |
| SCHEMBL7022401 | 0.87 | F2 (0.57) | F2PRSS1MASP2PRSS2PRSS3 | |
| SCHEMBL7021635 | 0.87 | F2 (0.58) | F2PRSS1MASP2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997474-B1 | Antithrombotic agents | PFIZER (US) | 2003-10-29 | — | — | EP | disclosed |