Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 18/20 | 0.73 |
| ▸ | TACR3 | P29371 | 1/20 | 0.56 |
| ▸ | RHOC | P08134 | 2/20 | 0.53 |
| ▸ | RHOA | P61586 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7611677 | 0.92 | TACR1 (0.83) | TACR1TACR3RHOCRHOA | |
| SCHEMBL7611683 | 0.92 | TACR1 (0.83) | TACR1TACR3RHOCRHOA | |
| SCHEMBL7610411 | 0.92 | TACR1 (0.86) | TACR1TACR3 | |
| SCHEMBL7610414 | 0.92 | TACR1 (0.86) | TACR1TACR3 | |
| Hydrochloric Acid SCHEMBL7618133 | 0.91 | TACR1 (0.84) | TACR1TACR3 | |
| Hydrochloric Acid SCHEMBL7618137 | 0.91 | TACR1 (0.84) | TACR1TACR3 | |
| SCHEMBL7614360 | 0.90 | TACR1 (0.71) | TACR1TACR3RHOCRHOA | |
| SCHEMBL8500550 | 0.90 | TACR1 (0.71) | TACR1TACR3RHOCRHOA | |
| SCHEMBL7614357 | 0.90 | TACR1 (0.71) | TACR1TACR3RHOCRHOA | |
| SCHEMBL8924388 | 0.89 | TACR1 (0.73) | TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935951-A | ANTAGONIST AGAINST SUBSTANCE P | NOVARTIS FINANCE CORPORATION (US) | 1999-08-10 | — | — | US | disclosed |