SCHEMBL8501966

CCCO[C@@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](C(O)C(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)O[C@H]1n1ccc(NC(=O)c2ccccc2)nc1=O

nearest known ligand 0.38

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	P2RY6	Q15077	3/20	0.38

▸	P2RY14	Q15391	2/20	0.38

▸	NT5E	P21589	1/20	0.36

▸	ABL1	P00519	1/20	0.34

▸	RIN1	Q13671	1/20	0.34

▸	POLB	P06746	1/20	0.33

▸	P2RY2	P41231	1/20	0.31

▸	P2RY4	P51582	1/20	0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8583477	0.89	P2RY6 (0.31)	P2RY6P2RY14NT5EP2RY2P2RY4
SCHEMBL6935455	0.88	P2RY6 (0.40)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL343674	0.87	POLB (0.45)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL6935052	0.84	P2RY6 (0.39)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL6935336	0.84	P2RY6 (0.38)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL6928627	0.83	P2RY6 (0.40)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL31160206	0.82	P2RY6 (0.39)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL31160167	0.82	P2RY6 (0.39)	P2RY6P2RY14NT5EABL1RIN1
SCHEMBL440942	0.82	POLB (0.38)	ABL1RIN1POLB
SCHEMBL30702563	0.81	P2RY6 (0.39)	P2RY6P2RY14NT5EABL1RIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5914396-A	2'-O-modified nucleosides and phosphoramidites	ISIS PHARMACEUTICALS, INC. (US)	1999-06-22	—	—	US	disclosed