Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27652216 | 0.88 | KMT2A (0.56) | KMT2AHSD17B14MAPTNPC1RAB9A | |
| SCHEMBL15100977 | 0.82 | KMT2A (0.56) | KMT2AHSD17B14MAPTNPC1RAB9A | |
| SCHEMBL28335196 | 0.79 | KMT2A (0.65) | KMT2AHSD17B14MAPTNPC1RAB9A | |
| SCHEMBL7079612 | 0.79 | KMT2A (0.65) | KMT2AHSD17B14MAPTNPC1RAB9A | |
| SCHEMBL30753851 | 0.79 | KMT2A (0.56) | KMT2AHSD17B14MAPTNPC1RAB9A | |
| SCHEMBL27581493 | 0.78 | HTT (0.53) | MAPTNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL1128807 | 0.77 | HPGD (0.58) | KMT2ANPC1RAB9ALMNAL3MBTL1 | |
| SCHEMBL29485021 | 0.77 | KMT2A (0.72) | KMT2AHSD17B14MAPTNPC1RAB9A | |
| SCHEMBL743166 | 0.77 | KMT2A (0.72) | KMT2AHSD17B14MAPTNPC1RAB9A | |
| SCHEMBL1156133 | 0.77 | KMT2A (0.72) | KMT2AHSD17B14MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888357-A1 | AZASPIRO DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034900-A1 | AZASPIRO DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1997-09-25 | — | — | WO | disclosed |