Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.52 |
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | PPARD | Q03181 | 4/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8165288 | 0.87 | ESR1 (0.70) | ESR1ESR2PPARGPPARDCHRM2 | |
| SCHEMBL6901973 | 0.86 | ESR1 (0.55) | ESR1ESR2PPARGPPARDFFAR1 | |
| SCHEMBL6900049 | 0.86 | ESR1 (0.55) | ESR1ESR2PPARGPPARDFFAR1 | |
| SCHEMBL8502244 | 0.82 | ESR1 (0.58) | ESR1ESR2CHRM2CHRM1KCNH2 | |
| SCHEMBL7504691 | 0.81 | ESR1 (0.59) | ESR1ESR2CHRM2CHRM1KCNH2 | |
| SCHEMBL3421120 | 0.78 | ESR1 (0.44) | ESR1ESR2DRD3DRD1DRD2 | |
| SCHEMBL7505415 | 0.78 | ESR1 (0.67) | ESR1ESR2PPARGCHRM2ADRA2A | |
| SCHEMBL7506971 | 0.78 | ESR1 (0.67) | ESR1ESR2PPARGCHRM2ADRA2A | |
| Hydrochloric Acid SCHEMBL7959989 | 0.78 | ESR1 (0.66) | ESR1ESR2PPARGCHRM2ADRA2A | |
| SCHEMBL8172028 | 0.77 | ESR1 (0.48) | ESR1ESR2FFAR1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934299-A1 | NOVEL $i(CIS)-3,4-CHROMAN DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES | NOVO NORDISK A/S (DK) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998018778-A1 | NOVEL CIS-3,4-CHROMAN DERIVATIVES USEFUL IN THE PREVENTION OR TREATMENT OF ESTROGEN RELATED DISEASES OR SYNDROMES | NOVO NORDISK A/S (DK) | 1998-05-07 | — | — | WO | disclosed |