⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8505757 | 0.96 | — | — | |
| SCHEMBL8504786 | 0.94 | — | — | |
| SCHEMBL8506376 | 0.94 | — | — | |
| SCHEMBL8504981 | 0.91 | — | — | |
| SCHEMBL8506480 | 0.91 | — | — | |
| SCHEMBL8505282 | 0.90 | — | — | |
| SCHEMBL8504694 | 0.89 | — | — | |
| SCHEMBL8506033 | 0.89 | — | — | |
| SCHEMBL8504494 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL8504522 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595924-B1 | PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LAB (US) | 1999-04-14 | — | — | EP | claimed |
| US-5459152-A | 3-(pyridin-3-yl)-7-(indol-3-yl)carbonyl-1H,3H-pyrrolo(1,2-c) thiazole derivatives; asthma | ABBOTT LABORATORIES (US) | 1995-10-17 | — | — | US | claimed |
| EP-0595924-B1 | PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LAB (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5459152-A | 3-(pyridin-3-yl)-7-(indol-3-yl)carbonyl-1H,3H-pyrrolo(1,2-c) thiazole derivatives; asthma | ABBOTT LABORATORIES (US) | 1995-10-17 | — | — | US | disclosed |