Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 6/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | APP | P05067 | 3/20 | 0.67 |
| ▸ | EGFR | P00533 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.51 |
| ▸ | GALR3 | O60755 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491252 | 0.83 | HTT (0.74) | HTTLMNAAPPEGFRMAPK1 | |
| SCHEMBL17803673 | 0.82 | HTT (0.81) | HTTLMNAAPPEGFRMAPK1 | |
| SCHEMBL8497438 | 0.81 | APP (0.69) | HTTLMNAAPPEGFRMAPK1 | |
| SCHEMBL8497590 | 0.81 | APP (1.00) | HTTLMNAAPPEGFRMAPK1 | |
| SCHEMBL8543033 | 0.79 | CCNC (0.71) | HTTLMNAAPPEGFRMAPK1 | |
| SCHEMBL8504270 | 0.78 | HTT (0.68) | HTTLMNAAPPEGFRMAPK1 | |
| SCHEMBL9609090 | 0.78 | HTT (0.64) | HTTLMNAAPPEGFRMAPK1 | |
| SCHEMBL9608072 | 0.77 | HTT (0.49) | HTTLMNAAPPEGFRMAPK1 | |
| SCHEMBL8497012 | 0.77 | HTT (0.65) | HTTLMNAAPPEGFRMAPK1 | |
| SCHEMBL17803677 | 0.76 | HTT (0.74) | HTTLMNAAPPEGFRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455371-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | SDS Biotech K. K. (JP) | 2012-05-23 | — | — | EP | disclosed |