Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TACR3 | P29371 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4556318 | 0.90 | KDM4E (0.55) | KDM4ESMN1; SMN2ALDH1A1TACR3MEN1 | |
| SCHEMBL3045119 | 0.90 | KDM4E (0.54) | KDM4ESMN1; SMN2ALDH1A1TACR3MEN1 | |
| SCHEMBL3155976 | 0.90 | KDM4E (0.54) | KDM4ESMN1; SMN2ALDH1A1TACR3MEN1 | |
| SCHEMBL2617528 | 0.89 | KDM4E (0.50) | KDM4ESMN1; SMN2ALDH1A1TACR3MEN1 | |
| SCHEMBL375146 | 0.89 | KDM4E (0.50) | KDM4ESMN1; SMN2ALDH1A1TACR3MEN1 | |
| SCHEMBL6011641 | 0.89 | KDM4E (0.50) | KDM4ESMN1; SMN2ALDH1A1TACR3MEN1 | |
| SCHEMBL8261052 | 0.89 | KDM4E (0.50) | KDM4ESMN1; SMN2ALDH1A1TACR3MEN1 | |
| SCHEMBL5692686 | 0.88 | KDM4E (0.48) | KDM4ESMN1; SMN2ALDH1A1TACR3MEN1 | |
| SCHEMBL3052299 | 0.86 | KDM4E (0.51) | KDM4ESMN1; SMN2ALDH1A1TACR3MEN1 | |
| SCHEMBL4981286 | 0.85 | KDM4E (0.48) | KDM4ESMN1; SMN2ALDH1A1TACR3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881002-A1 | HCV NS-3 serine protease inhibitors | Tibotec Pharmaceuticals Ltd. (IE) | 2008-01-23 | — | — | EP | disclosed |