Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.54 |
| ▸ | FNTA | P49354 | 6/20 | 0.45 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.45 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8505330 | 0.99 | CYP19A1 (0.53) | CYP19A1FNTAPGGT1BCPA1HRH3 | |
| SCHEMBL8505582 | 0.77 | NPC1 (0.39) | CYP19A1FNTAPGGT1BFNTB | |
| Hydrochloric Acid SCHEMBL8504372 | 0.77 | NPC1 (0.39) | CYP19A1FNTAPGGT1BFNTB | |
| Hydrochloric Acid SCHEMBL8135939 | 0.76 | FNTA (0.36) | CYP19A1FNTAPGGT1BFNTB | |
| SCHEMBL8368896 | 0.73 | CYP19A1 (0.61) | CYP19A1CPA1HRH3 | |
| SCHEMBL8582280 | 0.73 | NPC1 (0.42) | FNTAFNTB | |
| Hydrochloric Acid SCHEMBL8125957 | 0.72 | NPC1 (0.41) | FNTAFNTB | |
| SCHEMBL5892035 | 0.72 | CYP19A1 (0.43) | CYP19A1FNTAPGGT1BCPA1HRH3 | |
| SCHEMBL7053727 | 0.71 | CPA1 (0.71) | CYP19A1CPA1HRH3 | |
| Hydrochloric Acid SCHEMBL8368261 | 0.71 | CYP19A1 (0.42) | CYP19A1FNTAPGGT1BCPA1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981562-A | TREATMENT OF BLINDNESS TREATING BLINDNESS RELATED TO RETINAL VASCULARIZATION | MERCK & CO., INC. (US) | 1999-11-09 | — | — | US | claimed |