Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NT5E | P21589 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 4/20 | 0.42 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.42 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30999 | 0.94 | ING2 (0.48) | ALDH1A1HSD17B10LMNANT5EHPGD | |
| SCHEMBL9242875 | 0.94 | ING2 (0.48) | ALDH1A1HSD17B10LMNANT5EHPGD | |
| SCHEMBL29367149 | 0.94 | ING2 (0.48) | ALDH1A1HSD17B10LMNANT5EHPGD | |
| SCHEMBL772208 | 0.94 | ING2 (0.48) | ALDH1A1HSD17B10LMNANT5EHPGD | |
| SCHEMBL30057851 | 0.94 | ING2 (0.48) | ALDH1A1HSD17B10LMNANT5EHPGD | |
| SCHEMBL17627830 | 0.92 | ING2 (0.47) | ALDH1A1HSD17B10LMNANT5EHPGD | |
| SCHEMBL9960463 | 0.92 | ING2 (0.47) | ALDH1A1HSD17B10LMNANT5EHPGD | |
| SCHEMBL3222677 | 0.92 | ING2 (0.47) | ALDH1A1HSD17B10LMNANT5EHPGD | |
| SCHEMBL3309996 | 0.92 | ING2 (0.47) | ALDH1A1HSD17B10LMNANT5EHPGD | |
| SCHEMBL772207 | 0.92 | ING2 (0.47) | ALDH1A1HSD17B10LMNANT5EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5858326-A | CONTACTING AMYLOIDOGENIC PEPTIDE WITH AMYLOID-ENHANCING COMPOUND COMPRISING AROMATIC MOIETY AND AT LEAST TWO ANIONIC MOIETIES IN VITRO TO FORM AMYLOID FIBRILS | NEUROCHEM, INC. (CA) | 1999-01-12 | — | — | US | claimed |