Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.42 |
| ▸ | FASN | P49327 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8511755 | 0.88 | F2 (0.54) | EGLN1NPC1RAB9ASCN9AHPGDS | |
| SCHEMBL851898 | 0.83 | NPC1 (0.54) | EGLN1NPC1RAB9ASCN9AHPGDS | |
| SCHEMBL851787 | 0.77 | F2 (0.56) | EGLN1NPC1RAB9ASCN9AF2 | |
| SCHEMBL850777 | 0.74 | SCN9A (0.45) | EGLN1NPC1RAB9ASCN9AHPGDS | |
| SCHEMBL13875994 | 0.72 | PARP15 (0.43) | RAB9ASCN9APKM | |
| SCHEMBL851337 | 0.72 | NPC1 (0.71) | NPC1RAB9ASCN9AF2PRSS1 | |
| SCHEMBL851689 | 0.72 | F2 (0.52) | NPC1RAB9ASCN9AF2F10 | |
| SCHEMBL7122473 | 0.72 | EPHX2 (0.39) | EGLN1NPC1RAB9ASCN9AAR | |
| SCHEMBL851551 | 0.71 | ST14 (0.69) | EGLN1NPC1RAB9ASCN9AF2 | |
| SCHEMBL850974 | 0.71 | ST14 (0.69) | EGLN1NPC1RAB9ASCN9AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432556-A1 | PROTEASE INHIBITORS | Orion Corporation (FI) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |