Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 8/20 | 0.68 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.68 |
| ▸ | TNF | P01375 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | HTT | P42858 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28975960 | 0.80 | MAPK1 (0.69) | CYP11B1CYP11B2TNFMAPK1MEN1 | |
| SCHEMBL30310275 | 0.80 | MAPK1 (0.69) | CYP11B1CYP11B2TNFMAPK1MEN1 | |
| SCHEMBL15560485 | 0.79 | TNF (0.79) | CYP11B1CYP11B2TNFMAPK1MEN1 | |
| SCHEMBL4142913 | 0.79 | CYP11B1 (0.77) | CYP11B1CYP11B2TNFMAPK1MEN1 | |
| SCHEMBL30826274 | 0.79 | CYP11B1 (0.77) | CYP11B1CYP11B2TNFMAPK1MEN1 | |
| SCHEMBL15376499 | 0.79 | MAPK1 (0.78) | CYP11B1CYP11B2TNFMAPK1MEN1 | |
| SCHEMBL15382978 | 0.78 | MAPK1 (0.68) | CYP11B1CYP11B2TNFMAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL31253891 | 0.77 | CYP11B1 (0.75) | CYP11B1CYP11B2TNFMAPK1MEN1 | |
| Bromide SCHEMBL31253900 | 0.77 | CYP11B1 (0.75) | CYP11B1CYP11B2TNFMAPK1MEN1 | |
| SCHEMBL22684753 | 0.77 | CYP11B1 (0.67) | CYP11B1CYP11B2TNFMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968708-A | METAL PHTHALOCYANINE WITH MANGANESE, IRON, COBALT, ZINC OR CADMIUM METAL WITH ETHER OR SULFIDE SUBSTITUENTS | RICOH COMPANY, LTD. (JP) | 1999-10-19 | — | — | US | disclosed |