Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2403638 | 0.96 | BACE1 (0.73) | BACE1CYP3A4BLMXDHKDM4E | |
| SCHEMBL4809195 | 0.81 | BACE1 (1.00) | BACE1CYP3A4BLMXDHKDM4E | |
| SCHEMBL9242061 | 0.77 | BACE1 (0.78) | BACE1CYP3A4BLMXDHKDM4E | |
| SCHEMBL5907152 | 0.77 | BACE1 (0.74) | BACE1CYP3A4BLMXDHPOLB | |
| SCHEMBL10617521 | 0.77 | BACE1 (0.62) | BACE1CYP3A4BLMXDHKDM4E | |
| SCHEMBL4141928 | 0.76 | BACE1 (1.00) | BACE1CYP3A4BLMXDHSMN1; SMN2 | |
| SCHEMBL1123617 | 0.76 | BACE1 (0.76) | BACE1XDHKDM4EABL1RIN1 | |
| SCHEMBL5045779 | 0.76 | BACE1 (0.76) | BACE1XDHKDM4EABL1RIN1 | |
| SCHEMBL6474158 | 0.76 | BACE1 (0.76) | BACE1XDHKDM4EABL1RIN1 | |
| SCHEMBL15107929 | 0.75 | SMN1; SMN2 (0.69) | BACE1PKMTDP1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929597-A1 | SUPRAMOLECULAR POLYMER | DSM N.V. (NL) | 1999-07-21 | — | — | EP | disclosed |
| WO-1998014504-A1 | SUPRAMOLECULAR POLYMER | DSM N.V. (NL) | 1998-04-09 | — | — | WO | disclosed |