Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 18/20 | 0.63 |
| ▸ | PDE4B | Q07343 | 18/20 | 0.63 |
| ▸ | PDE4C | Q08493 | 18/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 18/20 | 0.63 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8507963 | 0.93 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8510031 | 0.92 | PDE4A (0.64) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7376075 | 0.92 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL8385725 | 0.91 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL8510077 | 0.91 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8511161 | 0.89 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7514013 | 0.88 | PDE4B (0.61) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7378155 | 0.87 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8511338 | 0.87 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DPDE5A | |
| SCHEMBL8532141 | 0.87 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4DPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861421-A | 4,4-(disubstituted) cyclohexan-1-one monomers and related compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-01-19 | — | — | US | claimed |
| US-5861421-A | 4,4-(disubstituted) cyclohexan-1-one monomers and related compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-01-19 | — | — | US | disclosed |