SCHEMBL8510220

SCHEMBL8510220

C[SiH2]N(C)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.44
HTT P42858 1/20 0.44
KMT2A Q03164 1/20 0.44
CA12 O43570 3/20 0.38
CA9 Q16790 3/20 0.38
CA2 P00918 2/20 0.38
FAAH O00519 1/20 0.38
PHGDH O43175 1/20 0.38
MGLL Q99685 1/20 0.38
CA1 P00915 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
LMNA P02545 1/20 0.37
ALDH1A1 P00352 4/20 0.35
TSHR P16473 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ALOX15 P16050 1/20 0.35
KCNN4 O15554 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3133237 0.80 MEN1 (0.46) MEN1HTTKMT2ACA12CA9
SCHEMBL10653957 0.77 MEN1 (0.42) MEN1HTTKMT2ACA12CA9
SCHEMBL14802977 0.76 MEN1 (0.42) MEN1HTTKMT2ACA12CA9
SCHEMBL16405945 0.76 MEN1 (0.42) MEN1HTTKMT2ACA12CA9
SCHEMBL28147756 0.76 MEN1 (0.42) MEN1HTTKMT2ACA12CA9
SCHEMBL16582959 0.74 KMT2A (0.41) MEN1HTTKMT2ACA12CA9
SCHEMBL19984964 0.70 MEN1 (0.38) MEN1HTTKMT2ACA12CA9
SCHEMBL20130855 0.70 MEN1 (0.38) MEN1HTTKMT2ACA12CA9
SCHEMBL7879117 0.69
SCHEMBL16187039 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103224510-B Alkoxy amino silane compound and application thereof 气体产品与化学公司 2016-08-03 CN claimed
CN-103224510-A Alkoxyaminosilane compounds and applications thereof AIR PROD & CHEM 2013-07-31 CN claimed
CN-114127197-A Curable resin composition, cured film formed therefrom, and electronic device having cured film 三星SDI株式会社 2022-03-01 CN disclosed
EP-3095788-A2 ORGANOAMINOSILANE PRECURSORS AND METHODS FOR DEPOSITING FILMS COMPRISING SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-11-23 EP disclosed
EP-2860182-A2 Organoaminosilane precursors and methods for depositing films comprising same AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-04-15 EP disclosed
CN-103224510-A Alkoxyaminosilane compounds and applications thereof AIR PROD & CHEM 2013-07-31 CN disclosed
US-20120135217-A1 Hybrid Polymers from Cyanates and Silazanes, Process for Their Production and Use CLARIANT INTERNATIONAL, LTD. (CH) 2012-05-31 US disclosed