SCHEMBL851205

SCHEMBL851205

CC(=O)OCC[C@@H](CC(=O)O)N(C(C)=O)c1ccc(CCS(=O)(=O)N2CCC3(CC2)N=C(c2ccc(F)c(C(F)(F)F)c2)NC3=O)c(C)c1

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTH1R Q03431 11/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL850402 0.92 PTH1R (0.48) PTH1R
SCHEMBL16087558 0.86 PTH1R (0.47) PTH1R
SCHEMBL16087651 0.83 PTH1R (0.47) PTH1R
SCHEMBL16087557 0.83 PTH1R (0.48) PTH1R
SCHEMBL849377 0.83 PTH1R (0.46) PTH1R
SCHEMBL847253 0.82 PTH1R (0.49) PTH1R
SCHEMBL848019 0.78 PTH1R (0.50) PTH1R
SCHEMBL16087551 0.77 PTH1R (0.51) PTH1R
SCHEMBL849291 0.76 PTH1R (0.46) PTH1R
SCHEMBL848965 0.75 PTH1R (0.57) PTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2433940-A1 SPIROIMIDAZOLONE DERIVATIVE Chugai Seiyaku Kabushiki Kaisha (JP) 2012-03-28 EP claimed