Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | CNR2 | P34972 | 4/20 | 0.63 |
| ▸ | CNR1 | P21554 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.55 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.55 |
| ▸ | VNN1 | O95497 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81347 | 0.96 | ATM (0.71) | ATMTDP1L3MBTL1POLBCNR2 | |
| SCHEMBL29658753 | 0.96 | ATM (0.71) | ATMTDP1L3MBTL1POLBCNR2 | |
| SCHEMBL15264066 | 0.92 | PARP1 (0.65) | ATMTDP1L3MBTL1POLBCNR2 | |
| SCHEMBL22175283 | 0.90 | PARP1 (0.59) | ATMTDP1L3MBTL1POLBCNR2 | |
| Benzophenone SCHEMBL11756762 | 0.90 | ATM (0.67) | ATMTDP1L3MBTL1POLBCNR2 | |
| SCHEMBL15686210 | 0.90 | ATM (0.67) | ATMTDP1L3MBTL1POLBCNR2 | |
| SCHEMBL822041 | 0.90 | PARP1 (0.63) | ATMTDP1L3MBTL1POLBCNR2 | |
| SCHEMBL186545 | 0.89 | PARP1 (0.68) | ATMTDP1L3MBTL1POLBCNR2 | |
| SCHEMBL29503529 | 0.89 | PARP1 (0.68) | ATMTDP1L3MBTL1POLBCNR2 | |
| SCHEMBL12792079 | 0.88 | CNR2 (0.57) | ATMTDP1L3MBTL1POLBCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143465-B2 | Soluble branched triaroylbenzene-based polymer and its synthetic method | THE HONG KONG UNIVERSITY OF SCIENCE & TECHNOLOGY (CN) | 2012-03-27 | — | — | US | disclosed |