SCHEMBL8512239

SCHEMBL8512239

[C]1=CC2CC1C1Cc3ccccc3CC21

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.32
KDM1A O60341 4/20 0.32
PNMT P11086 1/20 0.31
PLAU P00749 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL852834 0.70 IDO1 (0.39) IDO1KDM1APNMTPLAU
SCHEMBL29442080 0.70 IDO1 (0.39) IDO1KDM1APNMTPLAU
SCHEMBL2343768 0.59 IDO1 (0.46) IDO1PNMTPLAU
SCHEMBL4001927 0.58 IDO1 (0.36) IDO1PLAU
SCHEMBL2789125 0.56 PLAU (0.44) IDO1PNMTPLAU
SCHEMBL22361781 0.56 IDO1 (0.48) IDO1PLAU
SCHEMBL3947057 0.54 IDO1 (0.41) IDO1KDM1APLAU
SCHEMBL14231826 0.54 IDO1 (0.41) IDO1PLAU
SCHEMBL29539739 0.54 IDO1 (0.41) IDO1PLAU
SCHEMBL1415621 0.54 IDO1 (0.41) IDO1PLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2436702-B1 ISOBUTYLENE-BASED POLYMER AND METHOD FOR PRODUCING SAME JX NIPPON OIL & ENERGY CORP (JP) 2014-12-17 EP disclosed
US-20140194576-A1 RUBBER COMPOSITION, CROSSLINKED RUBBER COMPOSITION, PNEUMATIC TIRE, AND METHOD FOR PRODUCING ISOBUTYLENE POLYMER JX NIPPON OIL & ENERGY CORPORATION (JP) 2014-07-10 US disclosed
EP-2733172-A1 RUBBER COMPOSITION, CROSSLINKED RUBBER COMPOSITION, PNEUMATIC TIRE, AND METHOD FOR PRODUCING ISOBUTYLENE POLYMER JX Nippon Oil & Energy Corporation (JP) 2014-05-21 EP disclosed
US-8247508-B2 Isobutylene-based polymer and method for producing same JX NIPPON OIL & ENERGY CORPORATION (JP) 2012-08-21 US disclosed
US-20120136130-A1 ISOBUTYLENE-BASED POLYMER AND METHOD FOR PRODUCING SAME JX NIPPON OIL & ENERGY CORPORATION (JP) 2012-05-31 US disclosed