Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23854090 | 1.00 | CYP1A2 (0.67) | CYP1A2MAPK1SMN1; SMN2HSD17B10GLA | |
| SCHEMBL5032303 | 0.94 | CYP1A2 (0.59) | CYP1A2MAPK1SMN1; SMN2HSD17B10GLA | |
| SCHEMBL5032288 | 0.92 | CYP1A2 (0.57) | CYP1A2MAPK1SMN1; SMN2HSD17B10GLA | |
| SCHEMBL8514419 | 0.92 | CYP1A2 (0.57) | CYP1A2MAPK1SMN1; SMN2HSD17B10GLA | |
| SCHEMBL8947664 | 0.91 | — | — | |
| SCHEMBL8377176 | 0.91 | CYP1A2 (0.78) | CYP1A2MAPK1SMN1; SMN2GLALMNA | |
| SCHEMBL25212790 | 0.89 | CYP1A2 (0.55) | CYP1A2MAPK1SMN1; SMN2HSD17B10LMNA | |
| SCHEMBL9644791 | 0.89 | HSD17B10 (0.52) | CYP1A2MAPK1SMN1; SMN2HSD17B10GLA | |
| SCHEMBL5015980 | 0.88 | CYP1A2 (0.53) | CYP1A2MAPK1SMN1; SMN2HSD17B10LMNA | |
| SCHEMBL8685695 | 0.86 | GLA (0.57) | CYP1A2MAPK1SMN1; SMN2HSD17B10GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140377177-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. | 2014-12-25 | — | — | US | claimed |
| US-8758726-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2014-06-24 | — | — | US | claimed |
| US-20140017168-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2014-01-16 | — | — | US | claimed |
| US-8545809-B2 | Methods and compositions for improved 18F labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2013-10-01 | — | — | US | claimed |
| US-20120134920-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | IMMUNOMEDICS, INC. (US) | 2012-05-31 | — | — | US | claimed |
| CN-114072177-A | Site-specific kinetic inert conjugation of tags and/or vectors to target molecules, e.g., His-tagged proteins, via metal complex reagents | 马克思—普朗克科学促进协会公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-113993548-A | Site-specific kinetic inert conjugation of tags and/or vectors to target molecules, e.g., His-tagged proteins, via metal complex reagents | 马克思—普朗克科学促进协会公司 | 2022-01-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120134920-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, FCGRT, PAICS | CYP1A2 4880/4885MAPK1 4667/4885SMN1; SMN2 1351/4885 |
| US-20140017168-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, FCGRT, PAICS | CYP1A2 4880/4885MAPK1 4667/4885SMN1; SMN2 1351/4885 |
| US-20140377177-A1 | Methods and Compositions for Improved F-18 Labeling of Proteins, Peptides and Other Molecules | F13B, FCGRT, PAICS | CYP1A2 4880/4885MAPK1 4667/4885SMN1; SMN2 1351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.