Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.74 |
| ▸ | MAOA | P21397 | 1/20 | 0.74 |
| ▸ | GLA | P06280 | 5/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.64 |
| ▸ | GAPDH | P04406 | 5/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 2/20 | 0.55 |
| ▸ | CASP7 | P55210 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4818443 | 0.85 | MAOB (1.00) | MAOBMAOANPC1RAB9AMEN1 | |
| SCHEMBL15286102 | 0.85 | NPC1 (0.85) | MAOBGLAKDM4ENPC1RAB9A | |
| SCHEMBL14880118 | 0.83 | NPC1 (1.00) | MAOBGLAKDM4ENPC1RAB9A | |
| SCHEMBL20288536 | 0.81 | NPC1 (0.79) | MAOBMAOAGLAKDM4ENPC1 | |
| SCHEMBL16520513 | 0.81 | NPC1 (0.79) | MAOBGLAKDM4ENPC1RAB9A | |
| SCHEMBL18523591 | 0.81 | NPC1 (0.77) | MAOBGLAKDM4ENPC1RAB9A | |
| Acetic Acid SCHEMBL8512545 | 0.81 | MAOB (0.62) | MAOBMAOAGLAKDM4ENPC1 | |
| SCHEMBL28585595 | 0.81 | NPC1 (0.73) | MAOBMAOAGLAKDM4ENPC1 | |
| SCHEMBL31566290 | 0.81 | NPC1 (0.81) | MAOBGLAKDM4ENPC1RAB9A | |
| SCHEMBL8115599 | 0.81 | NPC1 (0.77) | MAOBGLAKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3269822-A1 | METHODS AND COMPOSITIONS TO DETECT A BIOLOGICAL ACTIVITY | 3M Innovative Properties Company (US) | 2018-01-17 | — | — | EP | disclosed |
| EP-2643471-B1 | METHODS AND COMPOSITIONS TO DETECT A BIOLOGICAL ACTIVITY | 3M INNOVATIVE PROPERTIES CO (US) | 2017-08-30 | — | — | EP | disclosed |
| EP-2643471-A1 | METHODS AND COMPOSITIONS TO DETECT A BIOLOGICAL ACTIVITY | 3M Innovative Properties Company (US) | 2013-10-02 | — | — | EP | disclosed |
| WO-2012071131-A1 | METHODS AND COMPOSITIONS TO DETECT A BIOLOGICAL ACTIVITY | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-05-31 | — | — | WO | disclosed |