Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 3/20 | 0.38 |
| ▸ | CDC7 | O00311 | 3/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL247690 | 1.00 | SOS1 (0.38) | SOS1CDC7DYRK3HPGDMAPT | |
| SCHEMBL8511130 | 0.96 | SOS1 (0.37) | SOS1CDC7DYRK3HPGDMAPT | |
| SCHEMBL8511133 | 0.96 | SOS1 (0.37) | SOS1CDC7DYRK3HPGDMAPT | |
| SCHEMBL8509684 | 0.90 | CDC7 (0.44) | CDC7DYRK3HPGDMAPTNPSR1 | |
| SCHEMBL246304 | 0.90 | DYRK3 (0.42) | CDC7DYRK3HPGDMAPTNPSR1 | |
| SCHEMBL8510193 | 0.90 | DYRK3 (0.42) | CDC7DYRK3HPGDMAPTNPSR1 | |
| SCHEMBL246096 | 0.90 | CDC7 (0.44) | CDC7DYRK3HPGDMAPTNPSR1 | |
| SCHEMBL8514561 | 0.90 | SOS1 (0.37) | SOS1DYRK3HPGDMAPTNPSR1 | |
| SCHEMBL8514555 | 0.90 | SOS1 (0.37) | SOS1DYRK3HPGDMAPTNPSR1 | |
| SCHEMBL8513536 | 0.86 | CDC7 (0.45) | CDC7DYRK3HPGDMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135989-A1 | AZAINDOLE DERIVATIVE | CRYSTALGENOMICS, INC. (KR) | 2012-05-31 | — | — | US | claimed |
| US-20120135989-A1 | AZAINDOLE DERIVATIVE | CRYSTALGENOMICS, INC. (KR) | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135989-A1 | AZAINDOLE DERIVATIVE | CDC7, CDCA2, CDC5L | SOS1 1989/4885CDC7 1/4885DYRK3 1263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.